منابع مشابه
Gram-positive phage-host interactions
Bacteriophage research has seen many peaks and troughs over the past century ascending with phage therapy and application in the early 1900’s; a research peak which was largely overshadowed by the dawning of the antibiotic era, and which has now deservedly regained attention as an approach against the problematic rise in antibiotic-resistant pathogenic bacteria. Following this initial scientifi...
متن کاملPhage–host interactions during pseudolysogeny
Although the study of phage infection has a long history and catalyzed much of our current understanding in bacterial genetics, molecular biology, evolution and ecology, it seems that microbiologists have only just begun to explore the intricacy of phage-host interactions. In a recent manuscript by Cenens et al. we found molecular and genetic support for pseudolysogenic development in the Salmo...
متن کاملStatistical structure of host-phage interactions.
Interactions between bacteria and the viruses that infect them (i.e., phages) have profound effects on biological processes, but despite their importance, little is known on the general structure of infection and resistance between most phages and bacteria. For example, are bacteria-phage communities characterized by complex patterns of overlapping exploitation networks, do they conform to a mo...
متن کاملExploiting what phage have evolved to control gram-positive pathogens
In the billion years that bacteriophage (or phage) have existed together with bacteria the phage have evolved systems that may be exploited for our benefit. One of these is the lytic system used by the phage to release their progeny from an infected bacterium. Endolysins (or lysins) are highly evolved enzymes in the lytic system produced to cleave essential bonds in the bacterial cell wall pept...
متن کاملFilamentous phage active on the gram-positive bacterium Propionibacterium freudenreichii.
We present the first description of a single-stranded DNA filamentous phage able to replicate in a gram-positive bacterium. Phage B5 infects Propionibacterium freudenreichii and has a genome consisting of 5,806 bases coding for 10 putative open reading frames. The organization of the genome is very similar to the organization of the genomes of filamentous phages active on gram-negative bacteria...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2015
ISSN: 1664-302X
DOI: 10.3389/fmicb.2015.00061